arXiv:2601.09758v1 Announce Type: cross Abstract: Batch effects represent a major confounder in genomic diagnostics. In copy number variant (CNV) detection from NGS, many algorithms compare read depth between test samples and a reference sample, assuming they are process-matched. When this assumption is violated, with causes ranging from reagent lot changes to multi-site processing, the reference becomes inappropriate, introducing false CNV calls or masking true pathogenic variants. Detecting such heterogeneity before downstream analysis is critical for reliable clinical interpretation. […]

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Reinforcement learning (RL) has become a key training step for improving mathematical reasoning in large language models (LLMs), but it often has high GPU memory usage, which makes it hard to use in settings with limited resources. To reduce these issues, we propose Evolution Strategies with Sharpness-Aware Maximization (ESSAM), a full parameter fine-tuning framework that tightly combines the zero-order search in parameter space from Evolution Strategies (ES) with the Sharpness-Aware Maximization (SAM) to improve generalization. We conduct fine-tuning […]

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arXiv:2601.02391v1 Announce Type: new Abstract: Wearable devices such as AI glasses are transforming voice assistants into always-available, hands-free collaborators that integrate seamlessly with daily life, but they also introduce challenges like egocentric audio affected by motion and noise, rapid micro-interactions, and the need to distinguish device-directed speech from background conversations. Existing benchmarks largely overlook these complexities, focusing instead on clean or generic conversational audio. To bridge this gap, we present WearVox, the first benchmark designed to rigorously evaluate […]

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arXiv:2601.00142v1 Announce Type: new Abstract: This paper compares three methodological categories of neural reasoning: LLM reasoning, supervised learning-based reasoning, and explicit model-based reasoning. LLMs remain unreliable and struggle with simple decision-making that animals can master without extensive corpora training. Through disjunctive syllogistic reasoning testing, we show that reasoning via supervised learning is less appealing than reasoning via explicit model construction. Concretely, we show that an Euler Net trained to achieve 100.00% in classic syllogistic reasoning can be trained […]

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Training a single network with multiple objectives often leads to conflicting gradients that degrade shared representations, forcing them into a compromised state that is suboptimal for any single task–a problem we term latent representation collapse. We introduce Domain Expansion, a framework that prevents these conflicts by restructuring the latent space itself. Our framework uses a novel orthogonal pooling mechanism to construct a latent space where each objective is assigned to a mutually orthogonal subspace. We validate our approach […]

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Active learning (AL) is a machine learning (ML) approach that strategically selects the most informative samples for annotation during training, aiming to minimize annotation costs. This strategy not only reduces labeling expenses but also results in energy savings during neural network training, thereby enhancing both data and energy efficiency. In this paper, we implement and evaluate various state-of-the-art acquisition functions, analyzing their accuracy and computational costs, while discussing the advantages and disadvantages of each method. Our findings reveal […]

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arXiv:2602.15559v1 Announce Type: cross Abstract: Adaptive randomized experiments update treatment probabilities as data accrue, but still require an end-of-study interval for the average treatment effect (ATE) at a prespecified horizon. Under adaptive assignment, propensities can keep changing, so the predictable quadratic variation of AIPW/DML score increments may remain random. When no deterministic variance limit exists, Wald statistics normalized by a single long-run variance target can be conditionally miscalibrated given the realized variance regime. We assume no interference, sequential […]

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arXiv:2602.11184v1 Announce Type: new Abstract: Mixture of Experts (MoE) models have achieved great success by significantly improving performance while maintaining computational efficiency through sparse expert activation. However, their enormous parameter sizes and memory demands pose major challenges for deployment in resource-constrained environments. Vector Quantization (VQ) offers a promising approach for ultra-low-bit compression in Large Language Models (LLMs) by leveraging a codebook, where weight vectors are mapped to the most similar discrete codewords. Yet, directly applying VQ to MoEs […]

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We’ve been experimenting with federated RL for heterogeneous robotic manipulation and ended up building a framework that separates representation federation from policy learning. Preprint is here. https://www.preprints.org/manuscript/202601.2257 I’d genuinely appreciate feedback on the design choices, especially around aggregation and stability. submitted by /u/EitherFox1242 [link] [comments]

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The design of environments plays a critical role in shaping the development and evaluation of cooperative multi-agent reinforcement learning (MARL) algorithms. While existing benchmarks highlight critical challenges, they often lack the modularity required to design custom evaluation scenarios. We introduce the Totally Accelerated Battle Simulator in JAX (TABX), a high-throughput sandbox designed for reconfigurable multi-agent tasks. TABX provides granular control over environmental parameters, permitting a systematic investigation into emergent agent behaviors and algorithmic trade-offs across a diverse spectrum […]

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