arXiv:2602.18473v1 Announce Type: new Abstract: Accurate analysis of medical time series (MedTS) data, such as electroencephalography (EEG) and electrocardiography (ECG), plays a pivotal role in healthcare applications, including the diagnosis of brain and heart diseases. MedTS data typically exhibit two critical patterns: temporal dependencies within individual channels and channel dependencies across multiple channels. While recent advances in deep learning have leveraged Transformer-based models to effectively capture temporal dependencies, they often struggle with modeling channel dependencies. This limitation stems […]

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arXiv:2509.19988v2 Announce Type: replace Abstract: Efficient design of genomic perturbation experiments is crucial for accelerating drug discovery and therapeutic target identification, yet exhaustive perturbation of the human genome remains infeasible due to the vast search space of potential genetic interactions and experimental constraints. Bayesian optimization (BO) has emerged as a powerful framework for selecting informative interventions, but existing approaches often fail to exploit domain-specific biological prior knowledge. We propose Biology-Informed Bayesian Optimization (BioBO), a method that integrates Bayesian […]

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How are you, hacker? 🪐 What’s happening in tech today, April 4, 2026? The HackerNoon Newsletter brings the HackerNoon homepage straight to your inbox. On this day, Martin Luther King Assassination in 1968, Microsoft is founded in 1975, Apollo 6 launched in 1968, and we present you with these top quality stories. Want to Have Successful OpenTelemetry Projects? Implement This One Tip By @nfrankel [ 4 Min read ] In this post, I want to tackle a real-world […]

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arXiv:2601.02769v1 Announce Type: new Abstract: We introduce Conformal Interquantile Regression (CIR), a conformal regression method that efficiently constructs near-minimal prediction intervals with guaranteed coverage. CIR leverages black-box machine learning models to estimate outcome distributions through interquantile ranges, transforming these estimates into compact prediction intervals while achieving approximate conditional coverage. We further propose CIR+ (Conditional Interquantile Regression with More Comparison), which enhances CIR by incorporating a width-based selection rule for interquantile intervals. This refinement yields narrower prediction intervals while […]

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arXiv:2603.06673v1 Announce Type: new Abstract: Spectroscopic imaging (SI) has become central to heritage science because it enables non-invasive, spatially resolved characterisation of materials in artefacts. In particular, attenuated total reflection Fourier transform infrared microscopy (ATR-$mu$FTIR) is widely used to analyse painting cross-sections, where a spectrum is recorded at each pixel to form a hyperspectral image (HSI). Interpreting these data is difficult: spectra are often mixtures of several species in heterogeneous, multi-layered and degraded samples, and current practice still […]

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Most demand gen programs are optimized to win over the marketer. But the marketer isn’t the decision. Here’s the structural problem nobody’s talking about — and what content strategy actually looks like when you solve for it. I was on a call recently with the VP of Growth at a B2B infrastructure company going through a significant rebrand. Sharp operator. Clear on her strategy. She was describing why she cared about content partnerships — not just ad placements, […]

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arXiv:2412.20495v2 Announce Type: replace-cross Abstract: The proliferation of real-world health data enables multi-institutional survival studies, yet privacy constraints preclude centralizing sensitive records. We present a privacy-preserving federated Kaplan–Meier framework based on threshold CKKS (Cheon-Kim-Kim-Song) homomorphic encryption that supports approximate floating-point computation and encrypted aggregation of per-time-point counts while exposing only public outputs. Sites compute aligned at-risk and event tallies on a shared time grid and encrypt compact vectors; a coordinator aggregates ciphertexts; and a decryptor committee produces partial […]

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arXiv:2602.20332v1 Announce Type: new Abstract: Advanced reasoning capabilities in Large Language Models (LLMs) have led to more frequent hallucinations; yet most mitigation work focuses on open-source models for post-hoc detection and parameter editing. The dearth of studies focusing on hallucinations in closed-source models is especially concerning, as they constitute the vast majority of models in institutional deployments. We introduce QueryBandits, a model-agnostic contextual bandit framework that adaptively learns online to select the optimal query-rewrite strategy by leveraging an […]

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Scientific Artificial Intelligence (AI) applications require models that deliver trustworthy uncertainty estimates while respecting domain constraints. Existing uncertainty quantification methods lack mechanisms to incorporate symbolic scientific knowledge, while neurosymbolic approaches operate deterministically without principled uncertainty modeling. We introduce the Constraint-Aware Neurosymbolic Uncertainty Framework (CANUF), unifying Bayesian deep learning with differentiable symbolic reasoning. The architecture comprises three components: automated constraint extraction from scientific literature, probabilistic neural backbone with variational inference, and differentiable constraint satisfaction layer ensuring physical consistency. Experiments […]

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arXiv:2604.06621v1 Announce Type: cross Abstract: Dr. David Blackwell was a mathematician and statistician of the first rank, whose contributions to statistical theory, game theory, and decision theory predated many of the algorithmic breakthroughs that define modern artificial intelligence. This survey examines three of his most consequential theoretical results the Rao Blackwell theorem, the Blackwell Approachability theorem, and the Blackwell Informativeness theorem (comparison of experiments) and traces their direct influence on contemporary AI and machine learning. We show that […]

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