arXiv:2602.05017v1 Announce Type: new Abstract: Agent-based cellular models simulate tissue evolution by capturing the behavior of individual cells, their interactions with neighboring cells, and their responses to the surrounding microenvironment. An important challenge in the field is scaling cellular resolution models to real-scale tumor simulations, which is critical for the development of digital twin models of diseases and requires the use of High-Performance Computing (HPC) since every time step involves trillions of operations. We hereby present a scalable […]

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AI Doesn’t Reduce Work—It Intensifies It Aruna Ranganathan and Xingqi Maggie Ye from Berkeley Haas School of Business report initial findings in the HBR from their April to December 2025 study of 200 employees at a “U.S.-based technology company”. This captures an effect I’ve been observing in my own work with LLMs: the productivity boost these things can provide is exhausting. AI introduced a new rhythm in which workers managed several active threads at once: manually writing code while […]

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Federated learning has emerged as a paradigm to train models collaboratively on inherently distributed client data while safeguarding privacy. In this context, personalized federated learning tackles the challenge of data heterogeneity by equipping each client with a dedicated model. A prevalent strategy decouples the model into a shared feature extractor and a personalized classifier head, where the latter actively guides the representation learning. However, previous works have focused on classifier head-guided personalization, neglecting the potential personalized characteristics in […]

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Custom Diffusion Models (CDMs) have gained significant attention due to their remarkable ability to personalize generative processes. However, existing CDMs suffer from catastrophic forgetting when continuously learning new concepts. Most prior works attempt to mitigate this issue under the sequential learning setting with a fixed order of concept inflow and neglect inter-concept interactions. In this paper, we propose a novel framework – Forget Less by Learning Together (FL2T) – that enables concurrent and order-agnostic concept learning while addressing […]

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Separating the contributions of individual chromogenic stains in RGB histology whole slide images (WSIs) is essential for stain normalization, quantitative assessment of marker expression, and cell-level readouts in immunohistochemistry (IHC). Classical Beer-Lambert (BL) color deconvolution is well-established for two- or three-stain settings, but becomes under-determined and unstable for multiplex IHC (mIHC) with K>3 chromogens. We present a simple, data-driven encoder-decoder architecture that learns cohort-specific stain characteristics for mIHC RGB WSIs and yields crisp, well-separated per-stain concentration maps. The […]

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How are you, hacker? 🪐 What’s happening in tech today, January 31, 2026? The HackerNoon Newsletter brings the HackerNoon homepage straight to your inbox. On this day, World War I saw its first major naval battle between Germany and Britain in 1915, NASA launched the first rocket in its Saturn I program in 1961, Communications Decency Act (CDA) was signed into law in 1996, and we present you with these top quality stories. The Crypto Sellout By @rayyoussef […]

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A decade ago, it would have been hard to believe that artificial intelligence could do what it can do now. However, it is this same power that introduces a new attack surface that traditional security frameworks were not built to address. As this technology becomes embedded in critical operations, companies need a multi-layered defense strategy that includes data protection, access control and constant monitoring to keep these systems safe. Five foundational practices address these risks. 1. Enforce strict […]

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