AI maps how a new antibiotic targets gut bacteria

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For patients with inflammatory bowel disease, antibiotics can be a double-edged sword. The broad-spectrum drugs often prescribed for gut flare-ups can kill helpful microbes alongside harmful ones, sometimes worsening symptoms over time. When fighting gut inflammation, you don’t always want to bring a sledgehammer to a knife fight. Researchers at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) and McMaster University have identified a new compound that takes a more targeted approach. The molecule, called enterololin, suppresses a […]

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Kernel Principal Component Analysis (PCA): Explained with an Example

Kernel Principal Component Analysis (PCA): Explained with an Example

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Dimensionality reduction techniques like PCA work wonderfully when datasets are linearly separable—but they break down the moment nonlinear patterns appear. That’s exactly what happens with datasets such as two moons: PCA flattens the structure and mixes the classes together.  Kernel PCA fixes this limitation by mapping the data into a higher-dimensional feature space where nonlinear patterns become linearly separable. In this article, we’ll walk through how Kernel PCA works and use a simple example to visually compare PCA […]

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